WebFeb 10, 2012 · Noradrenaline is an important neurotransmitter in the self-regulatory system of the brain (5). Brain noradrenergic dysregulation has been posited as a key causative … WebThe glial cell dysregulation hypothesis proposes that AD has its cause on changes on the activation of microglia and on impaired regulation, which become increasingly cytotoxic decreasing their ...

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WebApr 1, 2006 · Evidence from clinical and animal model studies for dysregulation of the noradrenergic system in depression is examined with respect to criteria generated by … WebThe above studies investigating the responsivity of the 5-HT system to provocation provide some support for the hypothesis drawn from the results of pharmacologic treatment trials and studies of biological markers that dysregulation of the 5-HT system may be involved in the pathogenesis of OC sympto … cheftreff

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Web• We compared sleep variables in 14 drug-free endogenous depressives and in 14 age- and insomnia-matched, nondepressed controls before and after brief rapid eye movement … WebDysregulation of the dopamine system is central to many models of the pathophysiology of psychosis in schizophrenia. However, emerging evidence suggests that this dysregulation is driven by the disruption of upstream circuits that provide afferent control of midbrain dopamine neurons. Furthermore, stress can profoundly disrupt this regulatory … WebIn this model, mesolimbic DA dysregulation is considered secondary to frontal dysfunction. A further recent elaboration on the DA hypothesis of schizophrenia considers the function of the mesolimbic DA system in assigning importance, or salience, to stimuli or ideas (Kapur 2003; Murray et al 2008). It is proposed that DA attaches a label (e.g ... fleischmann\u0027s corn starch recipes