P selectin mouse
WebThe Quantikine Mouse soluble P-Selectin (sP-Selectin) Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse sP-Selectin levels in cell culture supernates, serum, and EDTA plasma. It contains NS0-expressed recombinant mouse sP-Selectin and antibodies raised against the recombinant factor. WebCD62P is a 140 kD type I transmembrane glycoprotein, also known as P-selectin, platelet activation-dependent granule membrane protein (PADGEM), and GMP-140. It is expressed on activated platelets, megakaryocytes, and endothelial cells.
P selectin mouse
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WebMouse P-Selectin ELISA Kit (CD62P) (ab200014) is a single-wash 90 min sandwich ELISA designed for the quantitative measurement of P-Selectin (CD62P) protein in cit plasma, serum, cell culture supernatant, and cell culture extracts. It uses our proprietary SimpleStep ELISA® technology. Quantitate Mouse P-Selectin (CD62P) with 4.16 pg/ml ... WebMouse P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P), a member of the Selectin family, is a cell surface glycoprotein expressed by activated platelets and endothelial cells.
WebJun 4, 2009 · Plasma P-selectin has been shown to be elevated after stroke, and P-selectin deficiency and P-selectin antagonism protect from cerebral injury in models of MCAO. 23, … WebTo our surprise, we found that the E-selectin-binding form of P-selectin glycoprotein ligand-1 (PSGL-1) is expressed on the human bone-metastatic prostate tumor MDA PCa 2b cell line.
WebSelectins (L, E- and P-selectin) are a family of carbohydrate-binding cell adhesion molecules which play important roles in homing of lymphocytes, recruitment of leukocytes to sites of … WebP-Selectin, also known as GMP-140, LECAM-3, PADGEM, and CD62P, is a cell surface glycoprotein of the Selectin family and is expressed by activated platelets and endothelial cells (1-3). Mouse P-Selectin cDNA encodes a 768 amino acid (aa) type I transmembrane protein with a signal peptide, a large extracellular domain (ECD), a transmembrane ...
WebCD62P is a 140 kD type I transmembrane glycoprotein, also known as P-selectin, platelet activation-dependent granule membrane protein (PADGEM), and GMP-140. It is expressed on activated platelets, megakaryocytes, and endothelial cells.
WebFeb 2, 2024 · Moreover, 1.5-3-month-old P-selectin KO mice showed reduced IL-10-producing leukocytes in blood and a slightly reduced Treg population in the skin. With … olmsted dam and lock projectWebApr 20, 2024 · P-Selectin Antibody (1 E 3) is a mouse monoclonal IgG2a, so for a secondary antibody you would want to use an anti-mouse IgG secondary antibody conjugated to either alkaline phosphatase (AP) or horseradish peroxidase (HRP), depending on what detection method being used. We would recommend our mouse IgG binding protein conjugated to … olmsted democracyWebCD24 and CD162 (PSGL-1) are ligands of CD62P. mAb RB40.34 can block mouse P-selectin binding to its ligands in vitro and in vivo. The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max near 407 nm and Em Max near 421 nm, BD Horizon BV421 can be excited by the violet ... olmsted dam constructionWebP-selectin functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets. In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies. In unactivated platelets P-selectin is stored in α-granules . olmsted department of healthWebThe Mouse P-selectin - IgG Fusion Protein is composed of the signal sequence, the lectin domain, the EGF-like repeat, and the first two complement-binding domains of mouse P … olmsted county waste facilityWebMouse Immunogen Thrombin activated rat platelets Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Preparation The antibody was purified by … is amitiza otcWebJul 13, 2024 · Soluble P-selectin (sP-selectin) circulates in plasma of both humans and mice. In humans, a minor portion of sP-selectin is derived from alternative messenger RNA splicing that removes the exon encoding the transmembrane domain. 7-9 However, sP-selectin is primarily derived from proteolytic cleavage of the transmembrane protein, … is amit jain an american citizen